We have a Quiet Cool whole house fan and it is amazingly quiet. Works great during spring, summer (late at night) and fall. I use a box fan sorta the way you’re thinking about, but I installed even vents so I don’t have to open the garage. But we don’t have much in the way of humidity here, which I’m sure could be an issue. 

Ryan/// ~sigh~ I blew up another bowl. Moke told me "I made the inside bigger than the outside".