Start with what you know. Think about the drawer and the components you’ll use to build it. That will give you the outside dimension of the drawer, which will dictate the opening. From there you can size out the apron that will be proportionate to the height and style of the table as well as how the legs will attach. Another factor at that point will be any hardware used for the piece as that can also alter the design somewhat. Once you have the main box designed, determine how the top will blend with the piece and then look again at the legs to make sure their lines are in keeping with the design you’ve got so far.
I have a client that has brought me drawer pulls and asked me to design a piece around them. Fun project!
Artisan Woodworks of Texas- www.awwtx.com