John, a big yes to the kerf compensation built into LaserBurn. I "discovered" that after my first few panels. 
My diode laser has a rectangle when in focus and the kerf comp. makes a "more perfect" sized object. Way better, but not quite 100% perfect (the errors compound of course, just like wide box joints).

I've read, but not yet tried, to cut the rectangular parts laid out at a 45 degree angle to the lasers x/y axis. This makes all the cuts the same width WRT to the laser focus shape. Should make the fit even better.
For me, a great feature of LB software is the art library. I can add notes like the angle, etc.  so I don't forget about it a few minutes later. Also the ability to keep all the settings in a material library is great for the same reasons, keeping all the laser settings in place.